Cellular uptake of gold nanoparticles into normal and cancer cells

Jade Trono, Kazue Mizuno, Noritaka Yusa, Takehisa Matsukawa, Mitsuru Uesaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Gold nanoparticles intracellular uptake was investigated using both normal and cancer human cells. Cell uptake was analyzed using Atomic Absorption Spectrometry (AAS). It was found that combining 20nm gold nanoparticles with longer incubation time and lower concentration can optimize the uptake of gold nanoparticles by cancer cell. The findings of this study will help in the design and optimization of the nanoparticles uptake for therapeutic and diagnostic applications of X-ray Drug Delivery System.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationMicro- and Nanosystems in Medicine, Active Implants, Biosensors
PublisherSpringer Verlag
Pages202-205
Number of pages4
Edition8
ISBN (Print)9783642038860
DOIs
Publication statusPublished - 2009
Externally publishedYes
EventWorld Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors - Munich, Germany
Duration: 2009 Sep 72009 Sep 12

Publication series

NameIFMBE Proceedings
Number8
Volume25
ISSN (Print)1680-0737

Other

OtherWorld Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors
CountryGermany
CityMunich
Period09/9/709/9/12

Keywords

  • Dose enhancer
  • GNP contrast agent
  • Gold nanoparticle uptake
  • Radiosensitizer

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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