Cell signaling networks ontology

Takako Takai-Igarashi, Riichiro Mizoguchi

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Although databases for cell signaling pathways include numbers of reaction data of the pathways, the reaction data cannot be used yet to deduce biological functions from them. For the deduction, we need systematic and consistent interpretation of biological functions of reactions in cell signaling pathways in the context of "information transmission". To address this issue, we have developed a functional ontology for cell signaling pathways, Cell Signaling Network Ontology (CSN-Ontology), which provides framework for the functional interpretation presenting some important concepts as information, selectivity, movability, and signaling rules including passage of time.

Original languageEnglish
Pages (from-to)81-87
Number of pages7
JournalIn silico biology
Volume4
Issue number1
Publication statusPublished - 2004
Externally publishedYes

Keywords

  • Biological function
  • Cell signaling pathway
  • Ontology

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Computational Mathematics
  • Computational Theory and Mathematics

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