Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

Mustafa Şen, Kosuke Ino, Javier Ramón-Azcón, Hitoshi Shiku, Tomokazu Matsue

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

We present a chip device with an array of 900 gourd-shaped microwells designed to pair single cells of different types. The device consists of interdigitated array (IDA) electrodes and uses positive dielectrophoresis to trap cells within the microwells. Each side of a microwell is on a different comb of the IDA, so that cells of different types are trapped on opposite sides of the microwells, leading to close cell pairing. Using this device, a large number of cell pairs can be formed easily and rapidly, making it a highly attractive tool for controllable cell pairing in a range of biological applications.

Original languageEnglish
Pages (from-to)3650-3652
Number of pages3
JournalLab on a Chip
Volume13
Issue number18
DOIs
Publication statusPublished - 2013 Sep 21

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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