A cDNA encoding bovine tissue factor has been isolated from a γgt11 bovine adrenal cDNA library. The cDNA insert was 1877 base pairs with an open reading frame of 876 base pairs that encoded a presequence of 35 amino acids and a mature tissue factor of 257 amino acids. Bovine tissue factor had three potential N-glycosylation sites, four extracellular cysteine residues, a cytoplasmic cysteine residue, and one tripeptide tryptophan-lysine-serine motif. Identities of the amino acid sequences of the mature forms between the bovine tissue factor and each of human, mouse, and rabbit tissue factors were 70.4 %, 57.2 %, and 74.1 %, respectively.
|Number of pages||6|
|Journal||Biochemical and biophysical research communications|
|Publication status||Published - 1991 Dec 31|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology