X-Ray analysis of indole-3-acetic acid choline ester, a model compound for molecular recognition between the neurotransmitter acetylcholine and its esterase, shows that the quaternary trimethylammonium group is folded back to make a close contact with the indole ring through the cation-π interaction; 1H NMR spectroscopy confirms this type of interaction also occurs in solution.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1995 Dec 1|
ASJC Scopus subject areas
- Molecular Medicine