TY - JOUR
T1 - Catalytic enantioselective carbon-carbon bond forming reactions of masked acyl cyanides
AU - Umehara, Atsushi
N1 - Publisher Copyright:
© 2018 Society of Synthetic Organic Chemistry. All rights reserved.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2018
Y1 - 2018
N2 - Protected hydroxyl malononitriles, known as masked acyl cyanide (MAC) reagents are one of the most useful umpolung synthons to function as carbon monoxide equivalents with both nucleophilic and electorophilic reactivity. This dual reactivity, only characteristic in a few acyl anion equivalents, enables MAC reagents to afford a series of structurally diverse products by a one-carbon homologation under mild conditions. This review highlights the utility of MAC reagents in catalytic enantioselective carbon-carbon bond forming reactions that have been reported recently.
AB - Protected hydroxyl malononitriles, known as masked acyl cyanide (MAC) reagents are one of the most useful umpolung synthons to function as carbon monoxide equivalents with both nucleophilic and electorophilic reactivity. This dual reactivity, only characteristic in a few acyl anion equivalents, enables MAC reagents to afford a series of structurally diverse products by a one-carbon homologation under mild conditions. This review highlights the utility of MAC reagents in catalytic enantioselective carbon-carbon bond forming reactions that have been reported recently.
UR - http://www.scopus.com/inward/record.url?scp=85043449572&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85043449572&partnerID=8YFLogxK
U2 - 10.5059/yukigoseikyokaishi.76.255
DO - 10.5059/yukigoseikyokaishi.76.255
M3 - Article
AN - SCOPUS:85043449572
VL - 76
SP - 255
EP - 256
JO - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
JF - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
SN - 0037-9980
IS - 3
ER -