TY - JOUR
T1 - Carotid magnetic resonance imaging - A window to study atherosclerosis and identify high-risk plaques
AU - Oikawa, Minako
AU - Ota, Hideki
AU - Takaya, Norihide
AU - Miller, Zach
AU - Hatsukami, Thomas S.
AU - Yuan, Chun
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2009/10
Y1 - 2009/10
N2 - Despite recent advances in the understanding and etiology of cardiovascular disease, it remains the leading cause of morbidity and mortality worldwide. A great deal of research has been dedicated to investigating and identifying plaque instability: the so-called "vulnerable plaque". A reliable, in vivo, imaging method capable of identifying plaque characteristics associated with high-risk plaque will be immensely useful for evaluating plaque status and predicting future events. With excellent soft-tissue contrast and resolution, magnetic resonance imaging (MRI) has the ability to visualize features of vulnerable plaques, as well as perform longitudinal studies on the etiology, progression, and regression of atherosclerotic plaque. This review will cover the current state-of-the-art and new developments in carotid MRI to characterize atherosclerosis and its use in clinical diagnoses and longitudinal studies to understand mechanisms of lesion progression and regression.
AB - Despite recent advances in the understanding and etiology of cardiovascular disease, it remains the leading cause of morbidity and mortality worldwide. A great deal of research has been dedicated to investigating and identifying plaque instability: the so-called "vulnerable plaque". A reliable, in vivo, imaging method capable of identifying plaque characteristics associated with high-risk plaque will be immensely useful for evaluating plaque status and predicting future events. With excellent soft-tissue contrast and resolution, magnetic resonance imaging (MRI) has the ability to visualize features of vulnerable plaques, as well as perform longitudinal studies on the etiology, progression, and regression of atherosclerotic plaque. This review will cover the current state-of-the-art and new developments in carotid MRI to characterize atherosclerosis and its use in clinical diagnoses and longitudinal studies to understand mechanisms of lesion progression and regression.
KW - Atherosclerosis
KW - Cardiovascular diseases
KW - Carotid arteries
KW - Imaging
KW - Magnetic resonance imaging
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U2 - 10.1253/circj.CJ-09-0617
DO - 10.1253/circj.CJ-09-0617
M3 - Review article
C2 - 19755748
AN - SCOPUS:70349869229
VL - 73
SP - 1765
EP - 1773
JO - Circulation Journal
JF - Circulation Journal
SN - 1346-9843
IS - 10
ER -