Carotid Arterial Impedance During Oscillated Blood Flow

Shin–ichi Kobayashi, Shin–ichi Nitta, Tomoyuki Yambe, Shigeru Naganuma, Motonao Tanaka, Takeshi Kasai, Hiroyuki Hashimoto

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Abstract: Blood perfusion of systemic circulation is influenced by the physical characteristics of artery. Several investigations proposed that the physical parameters of vessels are determined by neurological factors, hormonal factors, and physical properties of arteries among others. In this study, arterial impedance was estimated because it may express the condition of vessels. To examine the change of arterial impedance according to the blood flow pattern, the typical sine wave blood flow (oscillated flow) was used during total cardiopulmonary bypass (CPB) because it is considered the most simple pulsatile flow. CPB using oscillated blood flow was performed in acute experiments on adult goats. Total systemic flow was controlled to remain at approximately 80 ml/min. Carotid arterial flow, aortic pressure, central venous pressure, and systemic flow were measured. Total peripheral resistance, carotid arterial resistance, systemic impedance, and carotid arterial impedance were calculated to evaluate blood flow distribution during CPB. This study suggested that the parameters of carotid arterial blood flow changed according to the change of flow frequency during oscillated blood flow. This change may occur because arterial impedance was influenced by flow frequency; therefore, the blood flow of the carotid artery was significantly changed according to the change of the frequency component of blood flow.

Original languageEnglish
Pages (from-to)627-632
Number of pages6
JournalArtificial Organs
Volume18
Issue number9
DOIs
Publication statusPublished - 1994 Sep

Keywords

  • Arterial impedance
  • Cardiopulmonary bypass
  • Carotid arterial flow
  • Frequency region of blood flow
  • Oscillated blood flow
  • Vibrating flow pump

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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