Carcinomatous change in the cranial metastasis from a metastasizing mixed tumor of the salivary gland -Case report-

Miki Fujimura; Takayuki Sugawara; Hirobumi Seki; Yasunari Otawara; Tsutomu Sakuma; Yoshishige Nakano; Takashi Yoshimoto

doi:10.2176/nmc.37.546

Carcinomatous change in the cranial metastasis from a metastasizing mixed tumor of the salivary gland -Case report-

Miki Fujimura, Takayuki Sugawara, Hirobumi Seki, Yasunari Otawara, Tsutomu Sakuma, Yoshishige Nakano, Takashi Yoshimoto

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

A 57-year-old female who had had a mixed tumor of the submandibular gland for 30 years presented with a cranial metastasis in the ipsilateral occipital region. Detailed histological examinations of the primary tumor failed to detect any carcinomatous component. In contrast, the metastasis contained a carcinomatous component. This histological discrepancy was confirmed by assessment of the expression of Ki-67 antigen in these tumor specimens and comparison with five typical benign mixed tumors. Cranial metastasis of a histologically benign mixed tumor is extremely rare, and a carcinomatous change in the metastatic tumor is apparently unique.

Original language	English
Pages (from-to)	546-550
Number of pages	5
Journal	Neurologia medico-chirurgica
Volume	37
Issue number	7
DOIs	https://doi.org/10.2176/nmc.37.546
Publication status	Published - 1997 Jul

Keywords

Cranial metastasis
Ki-67
Metastasizing mixed tumor
Pleomorphic adenoma
Skull tumor

ASJC Scopus subject areas

Surgery
Clinical Neurology

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Carcinomatous change in the cranial metastasis from a metastasizing mixed tumor of the salivary gland -Case report-. / Fujimura, Miki; Sugawara, Takayuki; Seki, Hirobumi; Otawara, Yasunari; Sakuma, Tsutomu; Nakano, Yoshishige; Yoshimoto, Takashi.

In: Neurologia medico-chirurgica, Vol. 37, No. 7, 07.1997, p. 546-550.

Research output: Contribution to journal › Article › peer-review

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AU - Sakuma, Tsutomu

AU - Nakano, Yoshishige

AU - Yoshimoto, Takashi

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Carcinomatous change in the cranial metastasis from a metastasizing mixed tumor of the salivary gland -Case report-

Abstract

Keywords

ASJC Scopus subject areas

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