Carboxylic acid-catalyzed highly efficient and selective hydroboration of alkynes with pinacolborane

Hon Eong Ho, Naoki Asao, Yoshinori Yamamoto, Tienan Jin

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

We have demonstrated for the first time that carboxylic acids are able to catalyze the direct hydroboration of various terminal and internal alkynes with pinacolborane without using any metal catalysts. This unprecedented catalytic hydroboration exhibits a broad functional groups compatibility, giving the corresponding alkenyl diboronates and monoboronates in good to high yields with exclusive regio- and stereoselectivities.

Original languageEnglish
Pages (from-to)4670-4673
Number of pages4
JournalOrganic letters
Volume16
Issue number17
DOIs
Publication statusPublished - 2014 Sep 5

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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