Abstract
We report on three cases of long-term dialysis patients with gynecological malignancies who were successfully treated with chemotherapy. Two epithelial ovarian carcinoma patients were treated with a single agent, carboplatin (100-200 mg/m2). One recurrent endometrial carcinoma patient was treated with carboplatin (200 mg/m2) and paclitaxel (135 mg/m 2). Hemodialysis was started 2 h after the carboplatin infusion and lasted 4 h in all three cases. All patients tolerated these therapies without significant myelosuppression or severe side-effects. Our findings suggest these regimens are feasible, and the combination of paclitaxel and carboplatin is effective chemotherapy when administered to long-term hemodialysis patients with recurrent endometrial carcinoma.
Original language | English |
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Pages (from-to) | 735-738 |
Number of pages | 4 |
Journal | Anti-cancer drugs |
Volume | 14 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2003 Oct |
Keywords
- Carboplatin
- Endometrial carcinoma
- Hemodialysis
- Ovarian carcinoma
- Paclitaxel
ASJC Scopus subject areas
- Oncology
- Pharmacology
- Pharmacology (medical)
- Cancer Research