Cancer-related stroke due to mural thrombus in the extracranial carotid artery

Daisuke Ando, Junpei Kobayashi, Hiroshi Kuroda, Masashi Aoki

Research output: Contribution to journalArticlepeer-review


A 41-year-old man was admitted to our hospital because of a cancer-related stroke (CRS) caused by a thrombus of the extracranial carotid artery. He had undergone neoadjuvant radiochemotherapy for metastatic colorectal adenocarcinoma. The serum D-dimer values were within the normal range. We treated him with intravenous unfractionated heparin followed by warfarin. There were no recurrent stroke events over six months. The leading cause of a CRS is an embolism caused by hypercoagulopathy, mainly represented by non-bacterial thrombotic endocarditis. However, it was unusual that, in the current case, a thrombus of the extracranial carotid artery was formed with no significant residual stenosis, thus resulting in an artery-toartery embolism.

Original languageEnglish
Pages (from-to)1497-1499
Number of pages3
JournalInternal Medicine
Issue number11
Publication statusPublished - 2016


  • Acute stroke
  • Cancer
  • Carotid ultrasound
  • Chemotherapy

ASJC Scopus subject areas

  • Internal Medicine


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