Can modulating corticotropin releasing hormone receptors alter visceral sensitivity?

S. Fukudo, K. Saito, Y. Sagami, M. Kanazawa

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

Activation of corticotropin releasing hormone (CRH) receptor 2 (CRH-R2) reduces visceral sensitivity induced by colorectal distension in conscious rats. This finding is relevant to the increased interest in the potential use of therapeutic agents that act on CRH receptors in the treatment of irritable bowel syndrome.

Original languageEnglish
Pages (from-to)146-148
Number of pages3
JournalGut
Volume55
Issue number2
DOIs
Publication statusPublished - 2006 Feb

ASJC Scopus subject areas

  • Gastroenterology

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