Calix[4]arene-based ditopic receptor for dicarboxylates

Takeharu Haino, Masaki Nakamura, Nobuki Kato, Miki Hiraoka, Yoshimasa Fukazawa

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


Shape-selective recognition for the dicarboxylates in DMSO can be attained by a new calix[4]arene-based receptor 1 having two urea groups. Biologically active chorismate selectively bound in 1 over its dehydrated derivative. Molecular mechanics calculations gave a plausible explanation for the selective binding.

Original languageEnglish
Pages (from-to)2281-2284
Number of pages4
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 2004 Feb 8
Externally publishedYes


  • Calix[4]arene
  • Host-guest chemistry
  • Hydrogen bonding
  • Molecular mechanics
  • Supramolecular chemistry

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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