C-H modification of 2-azaadamantane: Synthesis of C5-functionalized AZADOs for advanced use

Yusuke Sasano, Tomohiro Nishiyama, Masaki Tomizawa, Masatoshi Shibuya, Yoshiharu Iwabuchi

Research output: Contribution to journalArticle

Abstract

Regioselective C-H functionalization of N-protected 2-azaadamantane was achieved via a radical-induced bromination. The obtained 5-bromo-2-azaadamantane is readily transformed to arylated/alkylated 2-azaadamantane N-oxyls [AZADOs], which exhibit high catalytic activities for alcohol oxidation.

Original languageEnglish
Pages (from-to)2109-2118
Number of pages10
JournalHeterocycles
Volume87
Issue number10
DOIs
Publication statusPublished - 2013 Oct 10

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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