TY - JOUR
T1 - Breast-conserving surgery using supine magnetic resonance imaging in breast cancer patients receiving neoadjuvant chemotherapy
AU - Nakamura, Rikiya
AU - Nagashima, Takeshi
AU - Sakakibara, Masahiro
AU - Sangai, Takafumi
AU - Fujimoto, Hiroshi
AU - Arai, Manabu
AU - Shida, Takashi
AU - Kaneoya, Katsuhiko
AU - Ueda, Takuya
AU - Nakatani, Yukio
AU - Hashimoto, Hideyuki
AU - Miyazaki, Masaru
PY - 2008/6
Y1 - 2008/6
N2 - Background: Success of breast-conserving surgery (BCS) following neoadjuvant chemotherapy (NAC) depends on accurate assessment of the initial lesion. We developed a new procedure (NIPR) in which initial naked magnetic resonance images are projected onto the skin before BCS. Methods: Thirty-five breast cancer patients underwent supine oblique MRI of the operative area. In 20 DCIS patients, the metallic clips were reproduced by projection on the skin using NIPR, and discrepancies between the projection site and clip were measured on X-rays. Fifteen patients (T1;3,T2;8,T3;4 cases) treated with NIPR were compared to 20 (T1;5, T2;15 cases) treated using the conventional method with regard to excision area and additional excision rate of BCS after NAC. Results: The median discrepancy (linear distance) was 2.6 mm. NIPR significantly reduced the excision area and additional excision rate in T1 and T2 compared to the conventional method (P < 0.05). Conclusions: NIPR is a reliable technique for BCS following NAC with significant reductions in excision area and additional excision rate and superior cosmetic results.
AB - Background: Success of breast-conserving surgery (BCS) following neoadjuvant chemotherapy (NAC) depends on accurate assessment of the initial lesion. We developed a new procedure (NIPR) in which initial naked magnetic resonance images are projected onto the skin before BCS. Methods: Thirty-five breast cancer patients underwent supine oblique MRI of the operative area. In 20 DCIS patients, the metallic clips were reproduced by projection on the skin using NIPR, and discrepancies between the projection site and clip were measured on X-rays. Fifteen patients (T1;3,T2;8,T3;4 cases) treated with NIPR were compared to 20 (T1;5, T2;15 cases) treated using the conventional method with regard to excision area and additional excision rate of BCS after NAC. Results: The median discrepancy (linear distance) was 2.6 mm. NIPR significantly reduced the excision area and additional excision rate in T1 and T2 compared to the conventional method (P < 0.05). Conclusions: NIPR is a reliable technique for BCS following NAC with significant reductions in excision area and additional excision rate and superior cosmetic results.
KW - Breast carcinoma
KW - Mri
KW - Neoadjuvant chemotherapy
KW - Surgery
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U2 - 10.1016/j.breast.2007.10.007
DO - 10.1016/j.breast.2007.10.007
M3 - Article
C2 - 18024036
AN - SCOPUS:44349098577
VL - 17
SP - 245
EP - 251
JO - Breast
JF - Breast
SN - 0960-9776
IS - 3
ER -