Breast-conserving surgery using supine magnetic resonance imaging in breast cancer patients receiving neoadjuvant chemotherapy

Rikiya Nakamura, Takeshi Nagashima, Masahiro Sakakibara, Takafumi Sangai, Hiroshi Fujimoto, Manabu Arai, Takashi Shida, Katsuhiko Kaneoya, Takuya Ueda, Yukio Nakatani, Hideyuki Hashimoto, Masaru Miyazaki

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Background: Success of breast-conserving surgery (BCS) following neoadjuvant chemotherapy (NAC) depends on accurate assessment of the initial lesion. We developed a new procedure (NIPR) in which initial naked magnetic resonance images are projected onto the skin before BCS. Methods: Thirty-five breast cancer patients underwent supine oblique MRI of the operative area. In 20 DCIS patients, the metallic clips were reproduced by projection on the skin using NIPR, and discrepancies between the projection site and clip were measured on X-rays. Fifteen patients (T1;3,T2;8,T3;4 cases) treated with NIPR were compared to 20 (T1;5, T2;15 cases) treated using the conventional method with regard to excision area and additional excision rate of BCS after NAC. Results: The median discrepancy (linear distance) was 2.6 mm. NIPR significantly reduced the excision area and additional excision rate in T1 and T2 compared to the conventional method (P < 0.05). Conclusions: NIPR is a reliable technique for BCS following NAC with significant reductions in excision area and additional excision rate and superior cosmetic results.

Original languageEnglish
Pages (from-to)245-251
Number of pages7
JournalBreast
Volume17
Issue number3
DOIs
Publication statusPublished - 2008 Jun
Externally publishedYes

Keywords

  • Breast carcinoma
  • Mri
  • Neoadjuvant chemotherapy
  • Surgery

ASJC Scopus subject areas

  • Surgery

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