Brain death with calcium oxalate deposition in the kidney: Clue to the diagnosis of ethylene glycol poisoning

Shirushi Takahashi, Jun Kanetake, Yoshimasa Kanawaku, Masato Funayama

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

A young man presented to the emergency department with mental status changes, severe metabolic acidosis, and oliguria. Acute ethylene glycol intoxication was diagnosed. The patient suffered clinical brain death three days after admission despite intensive care and continuous hemodiafiltration. The patient died one month after admission. Autopsy revealed acute tubular necrosis of the kidneys with significant calcium oxalate depositions. The brain was markedly softening and with chronic meningoencephalitis and dural sinus thrombosis. We considered that the amount and the persistence of the calcium oxalate deposition in the kidney may afford a best clue to the postmortem diagnosis of ethylene glycol poisoning even in the chronic stage.

Original languageEnglish
Pages (from-to)43-45
Number of pages3
JournalLegal Medicine
Volume10
Issue number1
DOIs
Publication statusPublished - 2008 Jan
Externally publishedYes

Keywords

  • Brain death
  • Calcium oxalate deposition
  • Ethylene glycol poisoning

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Issues, ethics and legal aspects

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