TY - JOUR
T1 - Brain conditions mediate the association between aging and happiness
AU - Kokubun, Keisuke
AU - Nemoto, Kiyotaka
AU - Yamakawa, Yoshinori
N1 - Funding Information:
This work was funded by the ImPACT Program of Council for Science, Technology, and Innovation (Cabinet Office, Government of Japan) and supported by JSPS KAKENHI (Grant Number JP17H06151; JP18K18164).
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - As the population ages, the realization of a long and happy life is becoming an increasingly important issue in many societies. Therefore, it is important to clarify how happiness and the brain change with aging. In this study, which was conducted with 417 healthy adults in Japan, the analysis showed that fractional anisotropy (FA) correlated with happiness, especially in the internal capsule, corona radiata, posterior thalamic radiation, cingulum, and superior longitudinal fasciculus. According to previous neuroscience studies, these regions are involved in emotional regulation. In psychological studies, emotional regulation has been associated with improvement in happiness. Therefore, this study is the first to show that FA mediates the relationship between age and subjective happiness in a way that bridges these different fields.
AB - As the population ages, the realization of a long and happy life is becoming an increasingly important issue in many societies. Therefore, it is important to clarify how happiness and the brain change with aging. In this study, which was conducted with 417 healthy adults in Japan, the analysis showed that fractional anisotropy (FA) correlated with happiness, especially in the internal capsule, corona radiata, posterior thalamic radiation, cingulum, and superior longitudinal fasciculus. According to previous neuroscience studies, these regions are involved in emotional regulation. In psychological studies, emotional regulation has been associated with improvement in happiness. Therefore, this study is the first to show that FA mediates the relationship between age and subjective happiness in a way that bridges these different fields.
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U2 - 10.1038/s41598-022-07748-6
DO - 10.1038/s41598-022-07748-6
M3 - Article
C2 - 35277535
AN - SCOPUS:85126388825
SN - 2045-2322
VL - 12
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 4290
ER -