TY - JOUR
T1 - Brain atrophy during aging
T2 - A quantitative study with computed tomography
AU - Yamaura, H.
AU - Ito, M.
AU - Kubota, K.
AU - Matsuzawa, T.
PY - 1980
Y1 - 1980
N2 - Brain atrophy in 228 normal persons was quantitatively measured by computed tomography (CT), making use of computer programs available in the CT system. Pixels representing bone, brain, and cerebrospinal fluid in slices thru the head were counted by the computer. The volume percentage of the brain to the cranial cavity (Craniocerebral Index: CCI) was calculated from the pixel numbers. The CCI in 20 to 49-year-old adults was constant at 92 ± 3. This value was considered the standard of normal brain and the percentage of the subject's CCI to this value (Brain Volume Index: BVI) was calculated as the indicator of brain atrophy. The BVI was rather low in children (97 ± 5) and teenagers (96 ± 3), and decreased drastically with increasing age after 50 years. The BVI in the 80s was as low as 89 ± 6.
AB - Brain atrophy in 228 normal persons was quantitatively measured by computed tomography (CT), making use of computer programs available in the CT system. Pixels representing bone, brain, and cerebrospinal fluid in slices thru the head were counted by the computer. The volume percentage of the brain to the cranial cavity (Craniocerebral Index: CCI) was calculated from the pixel numbers. The CCI in 20 to 49-year-old adults was constant at 92 ± 3. This value was considered the standard of normal brain and the percentage of the subject's CCI to this value (Brain Volume Index: BVI) was calculated as the indicator of brain atrophy. The BVI was rather low in children (97 ± 5) and teenagers (96 ± 3), and decreased drastically with increasing age after 50 years. The BVI in the 80s was as low as 89 ± 6.
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U2 - 10.1093/geronj/35.4.492
DO - 10.1093/geronj/35.4.492
M3 - Article
C2 - 7400542
AN - SCOPUS:0018895543
VL - 35
SP - 492
EP - 498
JO - Journal of Gerontology: Social Sciences
JF - Journal of Gerontology: Social Sciences
SN - 0022-1422
IS - 4
ER -