Bottle-choice tests in sprague-dawley rats using liquid diets that differ in oil and sucrose contents

Fumiko Kimura, Risa Okada, Yasushi Endo, Kenshiro Fujimoto

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)


    Bottle choice tests using liquid diets were done with Sprague-Dawley (SD) rats. SD rats ingested more oil-and-sucrose-enriched milk (hi-fat) and less oil-enriched milk (hi-fat-no-carb) than sucrose-enriched (hi-carb) milk by two-bottle choice tests after they were habituated to liquid diets for 4 days. Chronic food restriction didn't increase hi-fat ingestion but hi-fat-no-carb. Rats ingested less without habituation, and overnight food deprivation increased intake. This increment was maintained after rats were free-fed. The difference in fat content of the maintenance diet had little effect on fat preference. These results showed SD rats prefer a sweet and fatty liquid diet than a sweet and lean liquid diet. Habituation and food restriction were more important than the composition of the maintenance diet to demonstrate a clear preference for the fatty liquid diet.

    Original languageEnglish
    Pages (from-to)1683-1690
    Number of pages8
    JournalBioscience, Biotechnology and Biochemistry
    Issue number8
    Publication statusPublished - 2003 Jan 1


    • Bottle choice test
    • Food preference
    • High fat diet
    • Optional food
    • Rats

    ASJC Scopus subject areas

    • Biotechnology
    • Analytical Chemistry
    • Biochemistry
    • Applied Microbiology and Biotechnology
    • Molecular Biology
    • Organic Chemistry


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