Bordetella pertussis infection in children with severe pneumonia, Philippines, 2012–2015

RITM-Tohoku Collaborative Research Group

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A case-comparison study was conducted based on an observational study of severe pneumonia among hospitalized children in the Philippines. The children, from 8 days to 13 years old and hospitalized with clinical diagnosis of severe or very severe pneumonia from August 2012 to February 2015, were recruited. Nasopharyngeal swabs were collected from 1152 cases and B. pertussis were detected from 34 cases by PCR. Pertussis-positive cases were more likely to have no fever, more than one week of coughing and breathing difficulty, decreased breathing sounds, and central cyanosis than pertussis- negative cases. The percentage of underweight was significantly higher in pertussis-positive cases than pertussis-negative cases. Pertussis-positive cases showed remarkably higher fatality rate than pertussis-negative cases. All of the fatal cases among pertussis-positive cases were less than 6 months old. More attention should be given to protect young infants from pertussis.

Original languageEnglish
Pages (from-to)993-996
Number of pages4
JournalVaccine
Volume35
Issue number7
DOIs
Publication statusPublished - 2017 Feb 15

Keywords

  • Bordetella pertussis
  • Philippines

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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