Abstract
An ethylene-vinyl alcohol copolymer (EVOH) was treated with a silane coupling agent and calcium silicate solutions, and then soaked in a simulated body fluid (SBF) with ion concentrations approximately equal to those of human blood plasma. A smooth and uniform bonelike apatite layer was successfully formed on both the EVOH plate and the EVOH-knitted fibers in SBF within 2 days. Part of the structure of the resulting apatite-EVOH fiber composite was similar to that of natural bone. If this kind of composite can be fabricated into a three-dimensional structure similar to natural bone, the resultant composite is expected to exhibit both mechanical properties analogous to those of natural bone and bone-bonding ability. Hence, it has great potential as a bone substitute.
Original language | English |
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Pages (from-to) | 1729-1735 |
Number of pages | 7 |
Journal | Biomaterials |
Volume | 24 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2003 May |
Externally published | Yes |
Keywords
- Apatite
- Biomimetic process
- Calcium silicate
- Ethylene-vinyl alcohol copolymer
- Silane coupling agent
ASJC Scopus subject areas
- Bioengineering
- Ceramics and Composites
- Biophysics
- Biomaterials
- Mechanics of Materials