Bonding of synthetic hydrogels with fibrin as the glue to engineer hydrogel-based biodevices

Kuniaki Nagamine, Kohei Okamoto, Hirokazu Kaji, Matsuhiko Nishizawa

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We show the fibrous protein fibrin can serve as biocompatible glue with which to bind synthetic cationic or anionic hydrogels together. Both the bonding to and detachment from the hydrogels by fibrin (gelation and degradation, respectively) proceeded enzymatically under physiological conditions. We built a hydrogel-based actuator to demonstrate the method.

Original languageEnglish
Pages (from-to)94-97
Number of pages4
JournalJournal of Bioscience and Bioengineering
Volume118
Issue number1
DOIs
Publication statusPublished - 2014 Jul

Keywords

  • Biocompatible glue
  • Fibrin
  • Hydrogel-based biodevice
  • Tissue engineering
  • Wet adhesion technique

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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