Blood vessels: Depiction at phase-contrast x-ray imaging without contrast agents in the mouse and rat - Feasibility study

A. Momose, T. Takeda, Y. Itai

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)

Abstract

The ability of phase-contrast x-ray imaging to depict blood vessels without contrast agents was tested by observing livers of a mouse and a rat with synchrotron x rays. Livers were excised by tying arteries and veins to prevent blood from flowing out of the liver. An x-ray interferometer was used to obtain x-ray phase contrast. With the technique of phase-shifting x-ray interferometry, the image mapping x-ray phase shift caused by a liver was measured. The x-ray phase shift caused by blood was substantially different from that caused by other soft tissues; consequently, trees of blood vessels were revealed on the image. Vessels with diameter smaller than 0.1 mm were recognized. This result allows new possibilities for investigation of the vascular system.

Original languageEnglish
Pages (from-to)593-596
Number of pages4
JournalRadiology
Volume217
Issue number2
DOIs
Publication statusPublished - 2000
Externally publishedYes

Keywords

  • Blood vessels
  • Raiography, phase contrast
  • Synchrotron

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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