Blood glucose measurement in vivo using hollow-fiber based, mid-infrared ATR probe with multi-reflection prism

Saiko Kino, Suguru Omori, Yuji Matsuura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

An attenuated-total-reflection (ATR), mid-infrared spectroscopy system that consists of hollow optical fibers, a trapezoidal multi-reflection ATR prism, and a conventional FT-IR spectrometer has been developed to measure blood glucose levels. Owing to the low transmission loss and high flexibility of the hollow-optical fiber, the system can measure any sites of the human body where blood capillaries are close to the surface of mucosa, such as inner lips. Using a multi-reflection prism brought about higher sensitivity, and the flat and wide contact surface of the prism resulted in higher measurement reproducibility. The results of in-vivo measurement of human inner lips showed the feasibility of the proposed system, and the measurement errors were within 20%.

Original languageEnglish
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI
EditorsIsrael Gannot
PublisherSPIE
ISBN (Electronic)9781628419368
DOIs
Publication statusPublished - 2016 Jan 1
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI - San Francisco, United States
Duration: 2016 Feb 132016 Feb 14

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9702
ISSN (Print)1605-7422

Other

OtherOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI
CountryUnited States
CitySan Francisco
Period16/2/1316/2/14

Keywords

  • Blood glucose measurement
  • hollow optical fibers
  • infrared spectroscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Kino, S., Omori, S., & Matsuura, Y. (2016). Blood glucose measurement in vivo using hollow-fiber based, mid-infrared ATR probe with multi-reflection prism. In I. Gannot (Ed.), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI [970209] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9702). SPIE. https://doi.org/10.1117/12.2216652