Bis-zirconium and bis-hafnium catalysts for the strong activation of carbonyl substrates

Hideo Hanawa, Satoshi Kii, Naoki Asao, Keiji Maruoka

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

(3,3'-Di-t-butyl-5,5'-dimethylbenzophenone-2,2'- dioxy)bis(triisopropoxyzirconium) and its hafnium derivative can be successfully utilized in organic synthesis as bimetallic Lewis acid catalysts. The high activation ability of such catalysts toward carbonyls is emphasized using several synthetic examples including the asymmetric allylation in comparison with the corresponding mono-Zr as well as bis-Ti catalysts. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)5543-5546
Number of pages4
JournalTetrahedron Letters
Volume41
Issue number29
DOIs
Publication statusPublished - 2000 Jul 15
Externally publishedYes

Keywords

  • Aldol reactions
  • Allylation
  • Asymmetric reactions
  • Zirconium and compounds

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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