Biosensing based on surface plasmon resonance of gold nanohole and nanoring arrays fabricated by a novel nanosphere lithography technique

Farah Fida, Ramin Banan-Sadeghian, Ahmad Reza Hajiaboli, Yahia Djaoued, Simona Badilescu, Subramanian Balaji, M. Kahrizi, Vo Van Truong

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    5 Citations (Scopus)

    Abstract

    An optical biosensor based on gold nanohole arrays was developed using a new nanosphere lithography technique. A vertical deposition method was used to deposit multilayers of a polystyrene (PS) - gold composite on a silanized glass substrate. The SEM images have shown that the gold nanohole and nanoring arrays are distributed uniformly on the substrate. The sensitivity of the gold Surface Plasmon Resonance (SPR) band to the environment was found to be dependent on the geometry of the array. The new nanostructures have been used as platforms for rapid screening of biomolecular interactions. Fibrinogen and biotin absorption studies conducted with the functionalized gold nanostructures demonstrated the feasibility of using them to monitor biomolecular interactions. The sensitivity was found to be around 300 nm·RIU-1, which is adequate for biosensing applications. The present technique has the advantage of simplicity; the structures can be prepared without any special equipment and a standard cell can be used for optical measurements.

    Original languageEnglish
    Title of host publicationProceedings - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008
    Pages114-119
    Number of pages6
    DOIs
    Publication statusPublished - 2008 Sep 26
    EventInternational Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008 - Bucharest, Romania
    Duration: 2008 Jun 292008 Jul 5

    Publication series

    NameProceedings - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008

    Conference

    ConferenceInternational Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008
    CountryRomania
    CityBucharest
    Period08/6/2908/7/5

    ASJC Scopus subject areas

    • Computational Theory and Mathematics
    • Information Systems
    • Biomedical Engineering

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  • Cite this

    Fida, F., Banan-Sadeghian, R., Hajiaboli, A. R., Djaoued, Y., Badilescu, S., Balaji, S., Kahrizi, M., & Truong, V. V. (2008). Biosensing based on surface plasmon resonance of gold nanohole and nanoring arrays fabricated by a novel nanosphere lithography technique. In Proceedings - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008 (pp. 114-119). [4561144] (Proceedings - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008). https://doi.org/10.1109/BIOTECHNO.2008.9