Biomedical imaging by Talbot-type X-ray phase tomography

Atsushi Momose, Wataru Yashiro, Masafumi Moritake, Yoshihiro Takeda, Kentaro Uesugi, Akihisa Takeuchi, Yoshio Suzuki, Makoto Tanaka, Tadashi Hattori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Citations (Scopus)

Abstract

An X-ray Talbot interferometer for X-ray phase imaging and tomography was constructed using an amplitude grating of a gold pattern 8 μm in pitch and 30 μm in height developed by X-ray lithography and gold electroplating. The effective area of the grating was 20 mm × 20 mm, and was fully illuminated by synchrotron radiation at beamline 20XU, SPring-8, Japan. Almost whole body of a fish 3 cm in length was observed by phase tomography. Resulting images obtained with 0.07 nm and 0.045 nm X-rays revealed organs with bones in the same view successfully. A preliminary result of the combination with an X-ray imaging microscope is also presented, which was attempted to attain a higher spatial resolution. Finally, prospects of the compatibility with a conventional X-ray generator are discussed for practical applications such as clinical diagnoses.

Original languageEnglish
Title of host publicationDevelopments in X-Ray Tomography V
DOIs
Publication statusPublished - 2006 Nov 13
Externally publishedYes
EventDevelopments in X-Ray Tomography V - San Diego, CA, United States
Duration: 2006 Aug 152006 Aug 17

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6318
ISSN (Print)1605-7422

Other

OtherDevelopments in X-Ray Tomography V
CountryUnited States
CitySan Diego, CA
Period06/8/1506/8/17

Keywords

  • Grating
  • Imaging
  • Phase
  • Talbot effect
  • Talbot interferometer
  • Tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Momose, A., Yashiro, W., Moritake, M., Takeda, Y., Uesugi, K., Takeuchi, A., Suzuki, Y., Tanaka, M., & Hattori, T. (2006). Biomedical imaging by Talbot-type X-ray phase tomography. In Developments in X-Ray Tomography V [63180T] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6318). https://doi.org/10.1117/12.678443