Biologie effects induced by micro/nano particles in vivo and in vitro study

T. Kazuchika, T. Noriyuki, U. Motohiro, A. Tsukasa, I. Roscca, T. Yasunori, T. Kazuyuki, W. Fumio

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The dependence of cytotoxicity on particle size in ceramic materials was investigated by biochemical functional analysis, in vitro using cells as probes and in vivo in animal implantation. The nanoparticles and carbon nano-tubes have the phlogogenic property according to their size. The nanoparticles were phagocytized by cells. The in vitro showed the cytotoxicity due to particle size effect. The results show that the cytotoxicity was induced due to the physical size effect in the range less than 100μm.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • Engineering(all)


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