Biological cell detection using ferromagnetic microbeads

T. Mitrelias, J. Palfreyman, Z. Jiang, J. Llandro, J. A.C. Bland, R. M. Sanchez-Martin, M. Bradley

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


The successful capture of different sized fluorescently labeled ferromagnetic microbeads by different cell lines is reported here. The cells have subsequently been analyzed by flow cytometry and the degree of uptake was found to be dependent on the bead size/concentration and the incubation time. In contrast to previous studies where superparamagnetic beads had mainly been used, we show that ferromagnetic beads, which have two orders of magnitude higher magnetic moments, can be successfully incubated with biological cells. The design of a "Y"-shaped microfluidic device that was successfully used to hydrodynamically focus and sort the fluorescent beads is also presented here.

Original languageEnglish
Pages (from-to)2862-2864
Number of pages3
JournalJournal of Magnetism and Magnetic Materials
Issue number2 SUPPL. PART 3
Publication statusPublished - 2007 Mar
Externally publishedYes


  • Biological cell
  • Ferromagnetic microbead
  • Microfluidic

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics


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