Biological activity of the polysaccharide produced by the marine phytoplankton porphyridium sp. and additive effect of slag on the polysaccharide production

Hiroko Sakamoto, Hideyuki Torada, Kentaro Goto, Yasue Nakamura, Toshiki Nakano, Toshiyasu Yamaguchi, Minoru Sato, Tadao Saito, Akira Taniguchi, Takehiko Yokoyama, Nobuhiro Kan-no, Eizou Nagahisa

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Marine phytoplankton Porphyridium sp. produced and secreted a mucilaginous polysaccharide in the incubation medium. The polysaccharide production was enhanced by the addition of slag at proper concentration. This polysaccharide showed a moderate mitogen activity, similar to dextran sulfate but lower than concanavalin A and lipopolysaccharide. Polysaccharide was found to have antitumor activity against Sarcoma 180 inoculated in the peritoneal cavity of ddY mice.

Original languageEnglish
Pages (from-to)475-481
Number of pages7
JournalTetsu-To-Hagane/Journal of the Iron and Steel Institute of Japan
Volume89
Issue number4
DOIs
Publication statusPublished - 2003 Apr

Keywords

  • Antitumor
  • Biological activity
  • Mitogen
  • Phytoplankton
  • Polysaccharide
  • Porphyridium sp.
  • Slag

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry
  • Metals and Alloys
  • Materials Chemistry

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