Biochemical and molecular biological analyses of space-flown nematodes in Japan, the first International Caenorhabditis elegans Experiment (ICE-First)

Akira Higashibata, Atsushi Higashitani, Ryota Adachi, Hiroaki Kagawa, Shuji Honda, Yoko Honda, Nahoko Higashitani, Yohei Sasagawa, Yutaka Miyazawa, Nathaniel J. Szewczyk, Catharine A. Conley, Nobuyoshi Fujimoto, Keiji Fukui, Toru Shimazu, Kana Kuriyama, Noriaki Ishioka

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The first International Caenorhabditis elegans Experiment (ICE-First) was carried out using a Russian Soyuz spacecraft from April 19-30, 2004. This experiment was apart of the program of the DELTA (Dutch Expedition for Life science Technology and Atmospheric research) mission, and the space agencies that participate in the International Space Station (ISS) program formed international research teams. A Japanese research team that conducted by Japan aerospace Exploration Agency (JAXA) investigated the following aspects of the organism: (1) whether meiotic chromosomal dynamics and apoptosis in the germ cells were normal under microgravity conditions, (2) the effect of the space flight on muscle cell development, and (3) the effect of the space flight on protein aggregation. In this article, we summarize the results of these biochemical and molecular biological analyses.

Original languageEnglish
Pages (from-to)159-163
Number of pages5
JournalMicrogravity Science and Technology
Volume19
Issue number5-6
DOIs
Publication statusPublished - 2007 Sep

ASJC Scopus subject areas

  • Modelling and Simulation
  • Engineering(all)
  • Physics and Astronomy(all)
  • Applied Mathematics

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