TY - JOUR
T1 - Biochemical and molecular biological analyses of space-flown nematodes in Japan, the first International Caenorhabditis elegans Experiment (ICE-First)
AU - Higashibata, Akira
AU - Higashitani, Atsushi
AU - Adachi, Ryota
AU - Kagawa, Hiroaki
AU - Honda, Shuji
AU - Honda, Yoko
AU - Higashitani, Nahoko
AU - Sasagawa, Yohei
AU - Miyazawa, Yutaka
AU - Szewczyk, Nathaniel J.
AU - Conley, Catharine A.
AU - Fujimoto, Nobuyoshi
AU - Fukui, Keiji
AU - Shimazu, Toru
AU - Kuriyama, Kana
AU - Ishioka, Noriaki
N1 - Funding Information:
Th f i experi n wa th pa t of th DELTA mission sponsored by the Space Research Organization of the Netherlands. We a e g a ef to Dr. M. Vso (NES: etre Ntol d’Etudes Spatiales) for his management and support. We acknowledge all the crew that assisted in this flight experiment in the Soyuz spacecraft and at the ISS. We t Drs. D. pt (C ES), L. Gra r, . Ecet, d G. Gsset (Uverste Pl Sabatier) for their kind support. We also thank the NASA Ames Research Center for providing the liquid medium for (CeMM). We pprecte te Erope Spce Agency supplying the KUBIKs. The strains used in this experiment were obtained from the Caenorhabditis Genetics Center funded by the National Institute of Health, National Center for Research Resources.
PY - 2007/9
Y1 - 2007/9
N2 - The first International Caenorhabditis elegans Experiment (ICE-First) was carried out using a Russian Soyuz spacecraft from April 19-30, 2004. This experiment was apart of the program of the DELTA (Dutch Expedition for Life science Technology and Atmospheric research) mission, and the space agencies that participate in the International Space Station (ISS) program formed international research teams. A Japanese research team that conducted by Japan aerospace Exploration Agency (JAXA) investigated the following aspects of the organism: (1) whether meiotic chromosomal dynamics and apoptosis in the germ cells were normal under microgravity conditions, (2) the effect of the space flight on muscle cell development, and (3) the effect of the space flight on protein aggregation. In this article, we summarize the results of these biochemical and molecular biological analyses.
AB - The first International Caenorhabditis elegans Experiment (ICE-First) was carried out using a Russian Soyuz spacecraft from April 19-30, 2004. This experiment was apart of the program of the DELTA (Dutch Expedition for Life science Technology and Atmospheric research) mission, and the space agencies that participate in the International Space Station (ISS) program formed international research teams. A Japanese research team that conducted by Japan aerospace Exploration Agency (JAXA) investigated the following aspects of the organism: (1) whether meiotic chromosomal dynamics and apoptosis in the germ cells were normal under microgravity conditions, (2) the effect of the space flight on muscle cell development, and (3) the effect of the space flight on protein aggregation. In this article, we summarize the results of these biochemical and molecular biological analyses.
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U2 - 10.1007/BF02919473
DO - 10.1007/BF02919473
M3 - Article
AN - SCOPUS:46149115149
VL - 19
SP - 159
EP - 163
JO - Microgravity Science and Technology
JF - Microgravity Science and Technology
SN - 0938-0108
IS - 5-6
ER -