Bioassisted selective-capture and release of nanoparticles toward application on microfluidic devices

Y. Shimada, M. Suzuki, M. Sugiyama, I. Kumagai, M. Umetsu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Peptides with affinity for inorganic materials hold promise for immobilizing functional nanostructures on a solid surface. In this study, a peptide with strict selective affinity for ZnO surfaces was utilized. We functionalized cadmium selenide (CdSe) nanoparticles by conjugating ZnO-binding peptides (ZnOBPs) on the surface of the nanoparticles and performed spontaneous and reversible patterning of ZnOBP-displayed nanoparticles on lithographed ZnO films. Conjugation of ZnOBPs on CdSe nanoparticles caused spontaneous adsorption of the nanoparticles on a ZnO film, and fluorescence and cathodoluminescence images clearly showed specific adsorption of nanoparticles on nano- and micrometer scales. The selectively-bound nanoparticles on ZnO films were completely released by changing the phosphate concentration in solution; such release did not require heat or mechanical applications. Our results show the potential of material-binding peptides for nanopatterning and dynamic microarray applications.

Original languageEnglish
Title of host publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages1745-1748
Number of pages4
DOIs
Publication statusPublished - 2011 Sep 1
Event2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
Duration: 2011 Jun 52011 Jun 9

Publication series

Name2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Other

Other2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
CountryChina
CityBeijing
Period11/6/511/6/9

Keywords

  • material-binding peptide
  • nanoparticles
  • reversible patterning

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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