PDMS-CaO-SiO2-TiO2 and PTMO-CaO-SiO 2-TiO2 hybrids formed bonelike apatite on their surfaces in simulated body fluid (SBF) and showed high deformability. The incorporation of CaO component was essential for them to show high apatite-forming ability in SBF, but CaO-containing hybrids showed a decrease in their mechanical strength by aging in the body environment. A CaO-free PDMS-TiO2 hybrid, in which the structure of TiO2 was controlled to be anatase by a hot-water treatment, also showed apatite-forming ability in SBF and high deformability. When PDMS is replaced with PTMO, the obtained PTMO-TiO 2 hybrid with a hot-water treatment shows apatite-forming ability in SBF and mechanical strength higher than that of the PDMS-TiO2 hybrid. When TiO2 is replaced with Ta2O5, a CaO-free PTMO-Ta2O5 hybrid shows apatite-forming ability in SBF without any treatment, as well as mechanical strength and Young's modulus analogous to those of human cancellous bones. These results indicate that a new kind of bioactive hybrid, which shows mechanical properties analogous to those of human bones and high durability in the body environment, can be obtained by controlling not only the compositions but also the structures of sol-gel-derived inorganic-organic hybrids.
|Number of pages||10|
|Journal||Annales de Chimie: Science des Materiaux|
|Publication status||Published - 2004 Jan 1|
ASJC Scopus subject areas
- Materials Chemistry