TY - GEN
T1 - Bioactive glass cloth that promotes new bone formation
AU - Minatoya, Tsutomu
AU - Furusawa, Toshitake
AU - Sato, Masaaki
AU - Matsushima, Yuta
AU - Unuma, Hidero
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - A new composition of bioactive glass was proposed that can be drawn into fibers, woven into cloth, and has appropriate alkali-releasing ability for bioactivity. The glass was drawn into fibers and woven into cloth, then the biological efficacy of the cloth was examined in in vivo tests. Bone defects made in tibial bones of Wistar rats were covered with the cloth just like "bandage" for two weeks. The cloth was found to promote new bone formation in the bone defects without causing any adverse effects. In contrast, excessive infection was recognized and new bone was not formed when cloth made of E-glass fibers was used. This was the first successful demonstration that glass cloth made of bioactive glass fibers assisted bone regeneration. The present glass cloth, therefore, is expected to be a promising material for "bone bandage" or porous scaffolds for bone tissue regeneration.
AB - A new composition of bioactive glass was proposed that can be drawn into fibers, woven into cloth, and has appropriate alkali-releasing ability for bioactivity. The glass was drawn into fibers and woven into cloth, then the biological efficacy of the cloth was examined in in vivo tests. Bone defects made in tibial bones of Wistar rats were covered with the cloth just like "bandage" for two weeks. The cloth was found to promote new bone formation in the bone defects without causing any adverse effects. In contrast, excessive infection was recognized and new bone was not formed when cloth made of E-glass fibers was used. This was the first successful demonstration that glass cloth made of bioactive glass fibers assisted bone regeneration. The present glass cloth, therefore, is expected to be a promising material for "bone bandage" or porous scaffolds for bone tissue regeneration.
KW - Bioactive glass
KW - Glass cloth
KW - New bone formation
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84871340906&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871340906&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.529-530.266
DO - 10.4028/www.scientific.net/KEM.529-530.266
M3 - Conference contribution
AN - SCOPUS:84871340906
SN - 9783037855171
T3 - Key Engineering Materials
SP - 266
EP - 269
BT - Bioceramics 24
PB - Trans Tech Publications Ltd
T2 - 24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012
Y2 - 21 October 2012 through 24 October 2012
ER -