The binaphthol (binol)-derived chiral titanium μ-oxo complex O is obtained accidentally upon toluene azetropy from a solution of binol and (PriO)2 TiCl2 after filtration of ms 4 Å and shown to be an efficient asymmetric catalyst for the glyoxylate-ene reaction with α-methylstyrene to give 98.7% entaniomeric excess and 88% yield even by the use of 0.2 mol% of the complex O.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1994 Dec 1|
ASJC Scopus subject areas
- Molecular Medicine