Bicarbonate decreases inhibitory effects of fluoride on acid production by Actinomyces naeslundii

Junko Kawashima, Kazuko Nakajo, Jumpei Washio, Hidetoshi Shimauchi, Nobuhiro Takahashi

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This study aimed to evaluate the effects of bicarbonate and fluoride on the acid production ability of Actinomyces naeslundii. In the presence of bicarbonate, the inhibitory effect of fluoride was decreased, suggesting that Actinomyces species have a unique mechanism to escape or weaken the inhibitory effect of fluoride. This might be relevant to that Actinomyces species has a bicarbonate-assimilating pathway for succinate production in addition to the glycolytic pathway.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2011
PublisherSpringer Japan
Pages189-191
Number of pages3
ISBN (Electronic)9784431540700
ISBN (Print)9784431540694
DOIs
Publication statusPublished - 2012 Jan 1

Keywords

  • Acid production
  • Actinomyces naeslundii
  • Bicarbonate
  • Fluoride
  • Mutans streptococci

ASJC Scopus subject areas

  • Dentistry(all)

Fingerprint Dive into the research topics of 'Bicarbonate decreases inhibitory effects of fluoride on acid production by Actinomyces naeslundii'. Together they form a unique fingerprint.

  • Cite this