Genotypes of early embryos obtained from mating Bh/+ quail were determined by chorio‐allantoic membrane grafting of their thigh skin, and the development of The Bh homozygous embryos was examined histologically. The Bh homozygous embryos died at an early stage of development (after 7 to 10 days of incubation) with a very high incidence of whole‐body hemorrhage (approximately 100%), but malformation of neural tubes was not always accompanied by Bh homozygosity. Degeneration of the liver was more frequently observed in homozygous embryos than in wild‐type and heterozygous embryos. The results suggest that the Bh gene causes whole‐body hemorrhage and subsequent death of homozygous embryos. In addition, our data indicate that Bh homozygote would develop brown feathers on theirskin if they were able to survive. © 1995 Wiley‐Liss, Inc.
ASJC Scopus subject areas
- Animal Science and Zoology