Beneficial effect of endovascular treatment on villalta score in Japanese patients with chronic iliofemoral venous thrombosis and post-thrombotic syndrome

Jin Ueda, Akihiro Tsuji, Takeshi Ogo, Ryotaro Asano, Nao Konagai, Shigefumi Fukui, Yoshiaki Morita, Tetsuya Fukuda, Satoshi Yasuda

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Background: Post-thrombotic syndrome (PTS), the most common complication of deep venous thrombosis (DVT), develops in ≥50% of patients with iliofemoral DVT. However, the benefit of endovascular treatment in Japanese patients with chronic DVT and PTS remains unclear. Methods and Results: Between June 2014 and May 2016, endovascular treatment was performed in 11 consecutive Japanese patients with chronic iliofemoral DVT and PTS refractory to anticoagulant therapy and elastic compression stockings. We evaluated the technical success rate, complications, patency, Villalta score, calf circumference, and popliteal vein reflux in both the acute stage (the day following endovascular treatment) and chronic stage (after 6 months). Imaging follow-up included venous duplex scanning and/or magnetic resonance venography. The technical success rate was 81.8%, without complications. In patients with successful intervention, the Villalta score improved significantly, from 9.0±3.7 preoperatively to 3.6±2.5 in the acute phase (P<0.01) and 2.9±2.1 in the chronic phase (P<0.001). The bilateral difference in lower thigh circumference also improved significantly, from 2.6±1.0 cm preoperatively to 1.4±1.0 cm in the chronic phase (P<0.001). However, popliteal vein reflux did not improve. In patients with successful intervention, venous patency rate was 100% at 6 months post-intervention. Conclusions: Endovascular treatment is safe and effective in Japanese patients with chronic iliofemoral DVT and PTS.

Original languageEnglish
Pages (from-to)2640-2646
Number of pages7
JournalCirculation Journal
Volume82
Issue number10
DOIs
Publication statusPublished - 2018
Externally publishedYes

Keywords

  • Chronic iliofemoral venous thrombosis
  • Endovascular treatment
  • Post-thrombotic syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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