Abstract
Bax protein-like immunoreactivity (Bax-ir) was examined in the perfusion-fixed, cryosectioned rat nervous system. In the central nervous system, hypothalamic neurons were the only neurons that exhibited Bax-ir in the cell body. Their axons traveled toward the median eminence, suggesting that the Bax-like immunoreactive (Bax-ir) hypothalamic neurons included neurosecretory ones. Bax-ir axons were observed in the solitary tract nucleus, and spinal and medullary dorsal hems. They appear to have been derived from Bax-ir primary sensory neurons in the viscerosensory nodose ganglion and somatosensory dorsal root and trigeminal ganglia. In the somatosensory ganglia, smaller cells exhibited stronger Bax-ir. Accordingly, the ir axons in the dorsal horn were most concentrated in lamina II.
Original language | English |
---|---|
Pages (from-to) | 37-40 |
Number of pages | 4 |
Journal | Neuroscience Letters |
Volume | 215 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1996 Aug 30 |
Externally published | Yes |
Keywords
- Bax
- Dorsal horn
- Hypothalamus
- Parabrachial nucleus
- Primary sensory neurons
- Solitary tract nucleus
ASJC Scopus subject areas
- Neuroscience(all)