Abstract
We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.
Original language | English |
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Pages (from-to) | 227-232 |
Number of pages | 6 |
Journal | Case Reports in Dermatology |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2012 Apr 20 |
Keywords
- Basosquamous cell carcinoma
- CD163<sup>+</sup> M2 macrophage
- Carcinogenesis
- Immunosuppressive cells
ASJC Scopus subject areas
- Dermatology