Basosquamous cell carcinoma developing from a renal transplantation recipient

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Abstract

We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.

Original languageEnglish
Pages (from-to)227-232
Number of pages6
JournalCase Reports in Dermatology
Volume4
Issue number3
DOIs
Publication statusPublished - 2012 Apr 20

Keywords

  • Basosquamous cell carcinoma
  • CD163<sup>+</sup> M2 macrophage
  • Carcinogenesis
  • Immunosuppressive cells

ASJC Scopus subject areas

  • Dermatology

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