An automated synthesis system for the production of 2-deoxy-2-[18F]fluoro-D-glucose (18FDG) has been developed. The system has been designed to be as convenient as possible for routine clinical use, and the whole synthetic procedure ranging from target irridiation to collection of a 18FDG solution has been completely automated by using a mucomputer as a controller and sensors of temperature, pressure, radioactivity and liquid level. This system provides 20-30 mCi of 18FDG in a sterile and pyrogen-free aqueous solution with a high radiochemical purity (over 98%) within 80 min after the 2-h irradiation with a current of 12 μA. The present automated synthesis system is suitable for routine production of 18FDG.
|Number of pages||10|
|Journal||The International Journal Of Applied Radiation And Isotopes|
|Publication status||Published - 1984 Jun|
ASJC Scopus subject areas
- Nuclear Energy and Engineering
- Radiology Nuclear Medicine and imaging