Autoimmune pancreatitis

Tooru Shimosegawa

Research output: Contribution to journalReview article

Abstract

Autoimmune pancreatitis (AIP) is a disease which is considered to develop on the background of autoimmune mechanism. It is characterized by unique findings in imagings, appearance of various autoantibodies and elevation of IgG and IgG4 in the blood, and pathologically by lymphoplasmacytic sclerosing pancreatitis (LPSP). It associates various extrapancreatic lesions that have pathological findings similar to the pancreas. Oral prednisolone is a very effective medicine and symptoms and clinical findings disappear soon after the start of steroid therapy. Focal type of AIP is sometimes very difficult to be differentiated from pancreato-biliary cancer that raises dispute over the use of steroids for the differential diagnosis.

Original languageEnglish
Pages (from-to)2393-2406
Number of pages14
JournalNippon rinsho. Japanese journal of clinical medicine
Volume66
Issue number12
Publication statusPublished - 2008 Dec

ASJC Scopus subject areas

  • Medicine(all)

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