Autoantibodies in neuromyelitis optica spectrum disorders

Ichiro Nakashima, Tetsuya Akaishi

Research output: Contribution to journalArticlepeer-review

Abstract

Neuromyelitis optica was previously considered a subtype of multiple sclerosis until a specific serum antibody, NMO-IgG, was discovered in 2004. In 2012, anti-MOG antibody was found specifically in the serum of patients whose presentation was similar to those with neuromyelitis optica. These autoantibodies are pathogenic and are important disease markers when reaching a diagnosis.

Original languageEnglish
Pages (from-to)297-304
Number of pages8
JournalBrain and Nerve
Volume70
Issue number4
Publication statusPublished - 2018 Apr
Externally publishedYes

Keywords

  • Aquaporin-4
  • Auto-antibody
  • Multiple sclerosis
  • Myelin oligodendrocyte glycoprotein
  • Neuromyelitis optica

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Autoantibodies in neuromyelitis optica spectrum disorders'. Together they form a unique fingerprint.

Cite this