Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult

T. Kawaguchi, Toshihiro Kumabe, M. Watanabe, T. Tominaga

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

A 22-year-old man presented with a rare case of atypical teratoid/ rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.

Original languageEnglish
Pages (from-to)1033-1038
Number of pages6
JournalActa neurochirurgica
Volume146
Issue number9
DOIs
Publication statusPublished - 2004 Sep

Keywords

  • Atypical teratoid/rhabdoid tumour
  • Chemotherapy
  • Leptomeningeal dissemination
  • Radiation

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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