ヘ テ ロ 原 子 置 換 ア ル キ ン を 用 い る ア ト ム エ コ ノミ ッ ク な ア ミ ド お よ び エ ス テ ル 形 成 反 応

Translated title of the contribution: Atom-economic amidation and esterification mediated by heteroatom-substituted terminal alkynes

Research output: Contribution to journalArticlepeer-review

Abstract

Amides and esters are ubiquitous substructures in life sciences, pharmaceuticals, and bioactive natural products. Although numerous coupling reagents for amidation and esterification have been developed to date, synthetic methodology avoiding poor atom economy and E-factor is still required. Recently, several groups have reported utility for the heteroatom-substituted terminal alkynes as coupling reagents, which react with carboxylic acids in a “click” manner. In this mini review, recent reports about atom-economic amide and ester synthesis via activated vinyl esters are highlighted.

Translated title of the contributionAtom-economic amidation and esterification mediated by heteroatom-substituted terminal alkynes
Original languageJapanese
Pages (from-to)790-791
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume79
Issue number8
DOIs
Publication statusPublished - 2021 Aug 1

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Atom-economic amidation and esterification mediated by heteroatom-substituted terminal alkynes'. Together they form a unique fingerprint.

Cite this