Asymmetric total synthesis of (-)-scabronine G via intramolecular double Michael reaction and Prins cyclization.

Naoki Kanoh, Kohei Sakanishi, Emiko Iimori, Ken'ichi Nishimura, Yoshiharu Iwabuchi

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

The enantioselective total synthesis of (-)-scabronine G is described. The key features of the present synthesis include the construction of a 5-6 ring system containing two quaternary carbon centers via a diastereoselective intramolecular double Michael reaction and the formation of a seven-membered ring using a Prins cyclization.

Original languageEnglish
Pages (from-to)2864-2867
Number of pages4
JournalOrganic letters
Volume13
Issue number11
Publication statusPublished - 2011 Jun 3

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Asymmetric total synthesis of (-)-scabronine G via intramolecular double Michael reaction and Prins cyclization.'. Together they form a unique fingerprint.

Cite this