Abstract
Pinned together: Asymmetric total synthesis of pinnaic acid was accomplished through a stereospecific route that features as key steps a Pd-catalyzed trimethylenemethane (TMM) [3+2] cyclization, a four-step tandem hydrogenation-cyclization, and cross-olefin-metathesis reactions (see scheme). (Chemical Equation Presented).
Original language | English |
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Pages (from-to) | 5746-5749 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 46 |
Issue number | 30 |
DOIs | |
Publication status | Published - 2007 Aug 3 |
Keywords
- Alkaloids
- Asymmetric synthesis
- Metathesis
- Natural products
- Total synthesis
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)