Abstract
Morphologically chiral crystals of sodium chlorate induce highly enantioselective synthesis. Thus the addition of diisopropylzinc to 2-(tert- butylethynyl)pyrimidine-5-carbaldehyde in the presence of d- and l-NaClO3 gives the (S)- and (R)-alkanol, respectively, in high yields and with high ee values.
Original language | English |
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Pages (from-to) | 1510-1512 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 39 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2000 Apr 17 |
Keywords
- Asymmetric synthesis
- Autocatalysis
- Molecular recognition
- Surface chemistry
- Zinc
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)