Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Takasuke Mukaiyama; Kento Ogata; Tsuyoshi Ono; Yujiro Hayashi

doi:10.1002/cctc.201402811

Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Takasuke Mukaiyama, Kento Ogata, Tsuyoshi Ono, Yujiro Hayashi

SCI - Chemistry

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.

Original language	English
Pages (from-to)	155-159
Number of pages	5
Journal	ChemCatChem
Volume	7
Issue number	1
DOIs	https://doi.org/10.1002/cctc.201402811
Publication status	Published - 2015 Jan

Keywords

Asymmetric reaction
Epoxide
Organocatalysis
Oxindole

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1002/cctc.201402811

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abstract = "The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.",

keywords = "Asymmetric reaction, Epoxide, Organocatalysis, Oxindole",

author = "Takasuke Mukaiyama and Kento Ogata and Tsuyoshi Ono and Yujiro Hayashi",

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AU - Mukaiyama, Takasuke

AU - Ogata, Kento

AU - Ono, Tsuyoshi

AU - Hayashi, Yujiro

PY - 2015/1

Y1 - 2015/1

N2 - The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.

AB - The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.

KW - Asymmetric reaction

KW - Epoxide

KW - Organocatalysis

KW - Oxindole

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M3 - Article

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ER -

Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Abstract

Keywords

ASJC Scopus subject areas

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