Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Takasuke Mukaiyama; Kento Ogata; Tsuyoshi Ono; Yujiro Hayashi

doi:10.1002/cctc.201402811

Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Takasuke Mukaiyama, Kento Ogata, Tsuyoshi Ono, Yujiro Hayashi

SCI - Chemistry

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.

Original language	English
Pages (from-to)	155-159
Number of pages	5
Journal	ChemCatChem
Volume	7
Issue number	1
DOIs	https://doi.org/10.1002/cctc.201402811
Publication status	Published - 2015 Jan

Keywords

Asymmetric reaction
Epoxide
Organocatalysis
Oxindole

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

Access to Document

10.1002/cctc.201402811

Cite this

@article{24b35a27b5e54b29a6136c0f371447d7,

title = "Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes",

abstract = "The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.",

keywords = "Asymmetric reaction, Epoxide, Organocatalysis, Oxindole",

author = "Takasuke Mukaiyama and Kento Ogata and Tsuyoshi Ono and Yujiro Hayashi",

note = "Publisher Copyright: {\textcopyright} 2015 Wiley-VCH Verlag GmbH & Co. KGaA.",

year = "2015",

month = jan,

doi = "10.1002/cctc.201402811",

language = "English",

volume = "7",

pages = "155--159",

journal = "ChemCatChem",

issn = "1867-3880",

publisher = "Wiley - VCH Verlag GmbH & CO. KGaA",

number = "1",

}

TY - JOUR

T1 - Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

AU - Mukaiyama, Takasuke

AU - Ogata, Kento

AU - Ono, Tsuyoshi

AU - Hayashi, Yujiro

PY - 2015/1

Y1 - 2015/1

N2 - The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.

AB - The asymmetric epoxidation of 2-oxoindoline-3-ylidene acetaldehydes, catalyzed by diarylprolinol silyl ether, has been developed. The reaction provides oxindole derivatives possessing chiral epoxides in good yield with good diastereoselectivity and excellent enantioselectivity.

KW - Asymmetric reaction

KW - Epoxide

KW - Organocatalysis

KW - Oxindole

UR - http://www.scopus.com/inward/record.url?scp=84920713787&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84920713787&partnerID=8YFLogxK

U2 - 10.1002/cctc.201402811

DO - 10.1002/cctc.201402811

M3 - Article

AN - SCOPUS:84920713787

VL - 7

SP - 155

EP - 159

JO - ChemCatChem

JF - ChemCatChem

SN - 1867-3880

IS - 1

ER -

Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this